As a SQL Server DBA, understanding the nuances of database settings is necessary for maintaining security and integrity. One such setting that often becomes a topic of discussion due to its significant impact on security is the TRUSTWORTHY database setting. The TRUSTWORTHY database setting in SQL Server is a configuration option that affects the security of certain database operations, particularly those involving code execution contexts. It plays a critical role in the security context of modules that use WITH EXECUTE AS, as well as CLR (Common Language Runtime) assemblies marked as EXTERNAL_ACCESS or UNSAFE.